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    李付广[中国农业科学院棉花研究所所长]

    李付广,男,1966年8月出生,河南延津县人,汉族, 中共党员,博士,研究员,博士生导师,国家杰出青年基金获得者,中国农业科学院棉花研究所所长,棉花生物学国家重点实验室主任,国家棉花产业联盟理事长,从事棉花遗传转化和分子改良研究工作,获国家科技进步二等奖2项、国家技术发明二等奖1项。

    现任中国农业科学院棉花研究所所长,郑州大学农学院院长。

    编辑摘要

    目录

    人物履历/李付广[中国农业科学院棉花研究所所长] 编辑

    2013年任中国农业科学院棉花研究所所长;  

    2004年任中国农业科学院棉花研究所副所长;

    2002年破格晋升研究员;

    2003年在中国农业科学院研究生院生物化学与分子生物学专业获得博士学位;

    1989年至今在中国农业科学院棉花研究所工作;

    何梁何利基金 何梁何利基金

    1989年于中国农业大学生物学院植物生理与生物化学专业获得学士学位;

    所获荣誉/李付广[中国农业科学院棉花研究所所长] 编辑

    2016获全国优秀科技工作者;

    2015中华农业英才奖;

    2012年获何梁何利基金科学与技术创新奖;

    2011年获得国家杰出青年基金

    2010年获得国家技术发明奖二等奖,排名第一;

    2009年获得国家科技进步二等奖,排名第二;

    2008年荣获中国科协求实杰出青年成果转化奖;

    2007年入选新世纪百千万人才工程国家级人选;

    2006年获国务院政府特殊津贴;

    2005年获得国家科技进步二等奖,排名第一;

    2005年荣获农业部有突出贡献的中青年专家称号;

    1.

    2016获全国优秀科技工作者;

    2.

    2015中华农业英才奖;

    3.

    2012年获何梁何利基金科学与技术创新奖;

    4.

    2011年获得国家杰出青年基金

    5.

    2010年获得国家技术发明奖二等奖,排名第一;

    6.

    2009年获得国家科技进步二等奖,排名第二;

    7.

    2008年荣获中国科协求实杰出青年成果转化奖;

    8.

    2007年入选新世纪百千万人才工程国家级人选;

    9.

    2006年获国务院政府特殊津贴;

    10.

    2005年获得国家科技进步二等奖,排名第一;

    11.

    2005年荣获农业部有突出贡献的中青年专家称号;

    研究成果/李付广[中国农业科学院棉花研究所所长] 编辑

    1. 棉花高频再生性状的遗传机制与新材料创制

    从棉花遗传转化中“转化体系不稳定、转化周期长”等关键技术瓶颈入手,以解决棉花组织培养再生体系中基因型限制、畸形胚频率高、遗传转化率低等问题。研究了棉花体细胞分化规律,发明了其分化性状的纯化方法,将生产品种中棉所24的体细胞分化率筛选纯化到95%、转化率提高到51.8%,使棉花成为可直接进行大规模基因功能验证的目标农作物,为全国从事棉花基础研究单位提供候选基因的快速功能验证创造了条件,先后为国内24个实验室转化验证候选基因156个,促进了基础研究成果在棉花遗传育种中的应用进程。[1]

    建立了棉花规模化遗传转化体系,克服了农杆菌介导法转化效率低、周期长的问题。创制抗虫种质材料1479份,上交国家中期库性状稳定材料865份,相当于我国棉花中期库50年来收集、引进、保存材料的1/10,对丰富棉花种质材料具有十分重要的意义;利用创制出的sGK9708、sGK中394、sGK中221等一系列具有重要育种价值的、不同基因型的、获得转基因安全评价证书的骨干种质材料,与育种家合作,先后培育出中棉所41等不同生态类型的转基因抗虫棉花新品种32个,转基因种质材料经全国育种家进一步引用,又衍生新品种20多个;培育的各类抗虫棉新品种累计推广面积1亿多亩,对促进国产抗虫棉从市场占有率的5%提升到97%以上发挥了重要作用,并创造了显著的社会经济效益。    

    2. 棉花基因组学研究

    参与主持了棉花基因组计划,并在国际上率先实施,先后完成了三个世界上最重要的棉种雷蒙徳氏棉(D5基因组)、亚洲棉(A2基因组)、陆地棉(A1A1D1D1基因组)的全基因组测序,填补了棉花没有参考基因组图谱的空白,为阐明棉花的起源、进化、揭示四倍体棉种及其他多倍体物种形成过程奠定了坚实的基础,同时也为我国在世界棉花基因组学研究方面占得先机。  

    主持项目/李付广[中国农业科学院棉花研究所所长] 编辑

    1. 国家自然基金-创新研究群体项目“棉花种质创新和高产分子育种”;  

    2. 国家杰出青年基金“棉花高频再生性状的遗传与应用研究”;  

    3. 国家自然基金-新疆联合基金重点项目“棉花水分高效利用关键基因的挖掘及抗旱材料创制[2]

    4. 国家自然基金-面上项目“来自棉花新WD-repeat蛋白与棉花抗早衰关系的研究”;  

    5. 863计划“优质高产棉花分子品种创制”  

    6. 973计划“棉花纤维品质功能基因组研究与分子改良”项目第五课题;  

    发表论文/李付广[中国农业科学院棉花研究所所长] 编辑

    Li FG, Fan GY, Lu CR, Xiao GH, Zou CS, Kohel RJ, Ma ZY, Shang HH, Ma XF, Wu JYet al: Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution. Nat Biotechnol 2015, 33(5):524-U242.

    Li FG, Fan GY, Wang KB, Sun FM, Yuan YL, Song GL, Li Q, Ma ZY, Lu CR, Zou CSet al: Genome sequence of the cultivated cotton Gossypium arboreum. Nature genetics 2014, 46(6):567-572.

    Wang K, Wang Z, Li F, Ye W, Wang J, Song G, Yue Z, Cong L, Shang H, Zhu Set al: The draft genome of a diploid cotton Gossypium raimondii. Nature genetics 2012, 44(10):1098-1103.

    Yang Z, Zhang C, Yang X, Liu K, Wu Z, Zhang X, Zheng W, Xun Q, Liu C, Lu Let al: PAG1, a cotton brassinosteroid catabolism gene, modulates fiber elongation. New Phytologist 2014, 203(2):437-448.

    Ge XY, Zhang CJ, Wang QH, Yang ZR, Wang Y, Zhang XY, Wu ZX, Hou YX, Wu JH, Li FG: iTRAQ Protein Profile Differential Analysis between Somatic Globular and Cotyledonary Embryos Reveals Stress, Hormone, and Respiration Involved in Increasing Plant let Regeneration of Gossypium hirsutum L. Journal of Proteome Research 2015, 14(1):268-278.

    You Q, Xu W, Zhang K, Zhang L, Yi X, Yao D, Wang C, Zhang X, Zhao X, Provart NJet al: ccNET: Database of co-expression networks with functional modules for diploid and polyploidGossypium. Nucleic Acids Res 2016:gkw910.

    Wang Y, Liang C, Wu S, Zhang X, Tang J, Jian G, Jiao G, Li F, Chu C: Significant Improvement of Cotton Verticillium Wilt Resistance by Manipulating the Expression of Gastrodia Antifungal Proteins. Mol Plant 2016, 9(10):1436-1439.

    Sun F, Liu CL, Zhang CJ, Qi WW, Zhang XY, Wu ZX, Kong DP, Wang QH, Shang HH, Qian XYet al: A conserved RNA recognition motif (RRM) domain of Brassica napus FCA improves cotton fiber quality and yield by regulating cell size. Mol Breeding 2012, 30(1):93-101.

    Yang Z, Li C, Wang Y, Zhang C, Wu Z, Zhang X, Liu C, Li F: GhAGL15s, preferentially expressed during somatic embryogenesis, promote embryogenic callus formation in cotton (Gossypium hirsutum L.). Molecular genetics and genomics : MGG 2014, 289(5):873-883.

    Cheng Y, Lu L, Yang Z, Wu Z, Qin W, Yu D, Ren Z, Li Y, Wang L, Li F: GhCaM7-like, a calcium sensor gene, influences cotton fiber elongation and biomass production. Plant Physiol Biochem 2016, 109:128-136.

    Zheng W, Zhang X, Yang Z, Wu J, Li F, Duan L, Liu C, Lu L, Zhang C: AtWuschel Promotes Formation of the Embryogenic Callus in Gossypium hirsutum. PLoS One 2014, 9(1):e87502.

    Bello B, Zhang X, Liu C, Yang Z, Wang Q, Zhao G, Li F: Cloning of Gossypium hirsutum Sucrose Non-Fermenting 1-Related Protein Kinase 2 Gene (GhSnRK2) and Its Overexpression in Transgenic Arabidopsis Escalates Drought and Low Temperature Tolerance. PLoS One 2014, 9(11):e112269.

    Zhu YX, Li FG: The Gossypium raimondii Genome, a Huge Leap Forward in Cotton Genomics. Journal of Integrative Plant Biology 2013, 55(7):570-571.

    Zhang XY, Yao DX, Wang QH, Xu WY, Wei Q, Wang CC, Liu CL, Zhang CJ, Yan H, Ling Yet al: mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage. PLoS One 2013, 8(1).

    Xu ZZ, Zhang CJ, Zhang XY, Liu CL, Wu ZX, Yang ZR, Zhou KH, Yang XJ, Li FG: Transcriptome Profiling Reveals Auxin and Cytokinin Regulating Somatic Embryogenesis in Different Sister Lines of Cotton Cultivar CCRI24. Journal of Integrative Plant Biology 2013, 55(7):631-642.

    Xu B, Gou J-Y, Li F-G, Shangguan X-X, Zhao B, Yang C-Q, Wang L-J, Yuan S, Liu C-J, Chen X-Y: A Cotton BURP Domain Protein Interacts With α-Expansin and Their Co-Expression Promotes Plant Growth and Fruit Production. Molecular Plant 2013, 6(3):945-958.

    Huang GQ, Gong SY, Xu WL, Li W, Li P, Zhang CJ, Li DD, Zheng Y, Li FG, Li XB: A Fasciclin-Like Arabinogalactan Protein, GhFLA1, Is Involved in Fiber Initiation and Elongation of Cotton. Plant Physiology 2013, 161(3):1278-1290.

    Guo FD, Liu CL, Xia H, Bi YP, Zhao CZ, Zhao SZ, Hou L, Li FG, Wang XJ: Induced Expression of AtLEC1 and AtLEC2 Differentially Promotes Somatic Embryogenesis in Transgenic Tobacco Plants. PLoS One 2013, 8(8).

    Zhang C, Yu S, Fan S, Zhang J, Li F: Inheritance of somatic embryogenesis using leaf petioles as explants in upland cotton. Euphytica 2011, 181(1):1-9.

    Yao D, Zhang X, Zhao X, Liu C, Wang C, Zhang Z, Zhang C, Wei Q, Wang Q, Yan Het al: Transcriptome analysis reveals salt-stress-regulated biological processes and key pathways in roots of cotton (Gossypium hirsutum L.). Genomics 2011, 98(1):47-55.

    Wang Q, Zhang X, Li F, Hou Y, Liu X: Identification of a UDP-glucose pyrophosphorylase from cotton (Gossypium hirsutum L.) involved in cellulose biosynthesis in Arabidopsis thaliana. Plant Cell Rep 2011.

    Wang Q, Li F, Zhang X, Zhang Y, Hou Y, Zhang S, Wu Z: Purification and Characterization of a CkTLP Protein from Cynanchum komarovii Seeds that Confers Antifungal Activity. PLoS One 2011, 6(2):e16930.

    Xu Z, Zhang C, Ge X, Wang N, Zhou K, Yang X, Wu Z, Zhang X, Liu C, Yang Zet al: Construction of a high-density linkage map and mapping quantitative trait loci for somatic embryogenesis using leaf petioles as explants in upland cotton (Gossypium hirsutum L.). Plant Cell Rep 2015:1-11.

    Meng X, Li F, Liu C, Zhang C, Wu Z, Chen Y: Isolation and Characterization of an ERF Transcription Factor Gene from Cotton (Gossypium barbadense L.). Plant Molecular Biology Reporter 2010, 28(1):176-183.

    1.

    Li FG, Fan GY, Lu CR, Xiao GH, Zou CS, Kohel RJ, Ma ZY, Shang HH, Ma XF, Wu JYet al: Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution. Nat Biotechnol 2015, 33(5):524-U242.

    2.

    Li FG, Fan GY, Wang KB, Sun FM, Yuan YL, Song GL, Li Q, Ma ZY, Lu CR, Zou CSet al: Genome sequence of the cultivated cotton Gossypium arboreum. Nature genetics 2014, 46(6):567-572.

    3.

    Wang K, Wang Z, Li F, Ye W, Wang J, Song G, Yue Z, Cong L, Shang H, Zhu Set al: The draft genome of a diploid cotton Gossypium raimondii. Nature genetics 2012, 44(10):1098-1103.

    4.

    Yang Z, Zhang C, Yang X, Liu K, Wu Z, Zhang X, Zheng W, Xun Q, Liu C, Lu Let al: PAG1, a cotton brassinosteroid catabolism gene, modulates fiber elongation. New Phytologist 2014, 203(2):437-448.

    5.

    iTRAQ Protein Profile Differential Analysis between Somatic Globular and Cotyledonary Embryos Reveals Stress, Hormone, and Respiration Involved in Increasing Plant let Regeneration of Gossypium hirsutum L

    6.

    You Q, Xu W, Zhang K, Zhang L, Yi X, Yao D, Wang C, Zhang X, Zhao X, Provart NJet al: ccNET: Database of co-expression networks with functional modules for diploid and polyploidGossypium. Nucleic Acids Res 2016:gkw910.

    7.

    Significant Improvement of Cotton Verticillium Wilt Resistance by Manipulating the Expression of Gastrodia Antifungal Proteins

    8.

    Sun F, Liu CL, Zhang CJ, Qi WW, Zhang XY, Wu ZX, Kong DP, Wang QH, Shang HH, Qian XYet al: A conserved RNA recognition motif (RRM) domain of Brassica napus FCA improves cotton fiber quality and yield by regulating cell size. Mol Breeding 2012, 30(1):93-101.

    9.

    GhAGL15s, preferentially expressed during somatic embryogenesis, promote embryogenic callus formation in cotton (Gossypium hirsutum L.)

    10.

    GhCaM7-like, a calcium sensor gene, influences cotton fiber elongation and biomass production

    11.

    AtWuschel Promotes Formation of the Embryogenic Callus in Gossypium hirsutum

    12.

    Cloning of Gossypium hirsutum Sucrose Non-Fermenting 1-Related Protein Kinase 2 Gene (GhSnRK2) and Its Overexpression in Transgenic Arabidopsis Escalates Drought and Low Temperature Tolerance

    13.

    The Gossypium raimondii Genome, a Huge Leap Forward in Cotton Genomics

    14.

    Zhang XY, Yao DX, Wang QH, Xu WY, Wei Q, Wang CC, Liu CL, Zhang CJ, Yan H, Ling Yet al: mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage. PLoS One 2013, 8(1).

    15.

    Transcriptome Profiling Reveals Auxin and Cytokinin Regulating Somatic Embryogenesis in Different Sister Lines of Cotton Cultivar CCRI24

    16.

    A Cotton BURP Domain Protein Interacts With α-Expansin and Their Co-Expression Promotes Plant Growth and Fruit Production

    17.

    A Fasciclin-Like Arabinogalactan Protein, GhFLA1, Is Involved in Fiber Initiation and Elongation of Cotton

    18.

    Induced Expression of AtLEC1 and AtLEC2 Differentially Promotes Somatic Embryogenesis in Transgenic Tobacco Plants

    19.

    Inheritance of somatic embryogenesis using leaf petioles as explants in upland cotton

    20.

    Yao D, Zhang X, Zhao X, Liu C, Wang C, Zhang Z, Zhang C, Wei Q, Wang Q, Yan Het al: Transcriptome analysis reveals salt-stress-regulated biological processes and key pathways in roots of cotton (Gossypium hirsutum L.). Genomics 2011, 98(1):47-55.

    21.

    Identification of a UDP-glucose pyrophosphorylase from cotton (Gossypium hirsutum L.) involved in cellulose biosynthesis in Arabidopsis thaliana

    22.

    Purification and Characterization of a CkTLP Protein from Cynanchum komarovii Seeds that Confers Antifungal Activity

    23.

    Xu Z, Zhang C, Ge X, Wang N, Zhou K, Yang X, Wu Z, Zhang X, Liu C, Yang Zet al: Construction of a high-density linkage map and mapping quantitative trait loci for somatic embryogenesis using leaf petioles as explants in upland cotton (Gossypium hirsutum L.). Plant Cell Rep 2015:1-11.

    24.

    Isolation and Characterization of an ERF Transcription Factor Gene from Cotton (Gossypium barbadense L.)

    主编专著/李付广[中国农业科学院棉花研究所所长] 编辑

    《棉花分子育种学》,2013年,中国农业大学出版社;

    《特种棉花及其产业化》2006年, 中国农业科学技术出版社

    《转基因抗虫棉丰产关键技术》2006年,中国三峡出版社 。

    1.

    《棉花分子育种学》,2013年,中国农业大学出版社;

    2.

    《特种棉花及其产业化》2006年, 中国农业科学技术出版社

    3.

    《转基因抗虫棉丰产关键技术》2006年,中国三峡出版社 。

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    参考资料
    [1]^引用日期:2016-12-08
    [2]^引用日期:2016-12-08
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